FOXO4-DRI

FOXO4-DRI Peptide – High-Purity Research Peptide for Cellular Senescence Studies

FOXO4-DRI peptide is a synthetic research peptide developed for advanced laboratory and preclinical researchfocused on cellular senescence, aging mechanisms, and apoptosis signaling pathways. FOXO4-DRI is widely studied for its role in disrupting it–p53 interactions in senescent cells, making it a valuable tool in aging and longevity research models.

FOXO4-DRI is not a drug, supplement, or therapeutic agent.
FOXO4-DRI peptide is intended strictly for laboratory research use only.

What Is it?

FOXO4-DRI is a cell-penetrating peptide derived from the FOXO4 transcription factor, engineered to interfere with the binding between FOXO4 and p53 in senescent cells. In research settings, this interaction is known to contribute to the survival of senescent cells, which accumulate with aging and cellular stress.

By disrupting this interaction, FOXO4-DRI peptide is studied for its ability to selectively affect senescent cells while sparing normal, non-senescent cells in controlled experimental models.

FOXO4-DRI Mechanism of Action (Research Context)

In laboratory studies,  is researched for its capacity to:

• Disrupt protein binding
• Promote p53 nuclear exclusion in senescent cells
• Induce apoptosis selectively in senescent cell models
• Support research into senolytic mechanisms
• Help model aging-related cellular accumulation

These properties make this peptide an important research tool for cellular aging and senescence pathway analysis.

FOXO4-DRI Peptide Specifications

• Product Name: FOXO4-DRI Peptide
• Category: Research Peptide
• Peptide Type: FOXO4-derived, cell-penetrating peptide
• Purity: ≥99% (HPLC-verified)
• Form: Lyophilized powder
• Appearance: White to off-white solid
• Solubility: Sterile water, PBS, or DMSO (research use only)

High purity ensures experimental accuracy and reproducibility.