GDF-15

(Growth Differentiation Factor-15) – Research Protein for Cellular Stress & Metabolic Studies

GDF-15, also known as Growth Differentiation Factor-15, is a recombinant research protein used in laboratory and preclinical studies to investigate cellular stress responses, metabolism, and tissue signaling pathways. Part of the TGF-β superfamily, this protein is widely studied in cellular homeostasis and inflammation research.

This product is for laboratory research use only and is not intended for human or animal consumption, therapeutic, or diagnostic applications.

Overview of GDF-15

GDF-15 is a stress-responsive factor expressed in multiple tissues, including the liver, heart, and immune system. In research, it is used to examine cellular responses to stress, metabolic regulation, and signaling pathways, providing insight into tissue homeostasis and disease models in vitro.

Biological Role (Research Context)

In laboratory studies, the factor interacts with its receptor GFRAL and modulates downstream signaling involved in:

• Cellular stress adaptation

• Inflammatory and immune responses

• Energy metabolism and tissue homeostasis

This makes GDF-15 a valuable tool for mechanistic studies of metabolism and cellular stress in experimental models.

Key Research Applications

GDF-15 is commonly utilized in studies of:

• Metabolic and energy homeostasis

• Cellular stress and inflammation modeling

• Tissue signaling and adaptive mechanisms

• Comparative analysis with other TGF-β family proteins

Its high purity ensures reliable and reproducible results in in vitro and preclinical research.

Product Specifications

• Product Name: Growth Differentiation Factor-15

• Category: Research Protein / Peptide

• Protein Family: TGF-β superfamily

• Purity: ≥99% (HPLC-verified)

• Form: Lyophilized powder

• Appearance: White to off-white solid

• Solubility: Soluble in sterile water, PBS, or standard laboratory buffers

Storage & Handling

• Store lyophilized material at -20°C or below

• Reconstitute under sterile conditions

• Aliquot after reconstitution to prevent repeated freeze-thaw cycles

• Use appropriate PPE and follow standard laboratory handling procedures

Research Use Disclaimer

This protein is supplied for laboratory research only.
It is not for human or animal use, nor for therapeutic or diagnostic purposes. All experimentation should be conducted by qualified professionals in appropriately equipped laboratories