PEPTIDE SCINESES HNGKONG, wholesale peptides, sarms

Buy Peptides for Scientific Research and Development.

Verification: 9fed31eec3120502

-
-
RAD-140 Testolone

RAD-140 Testolone

RAD-140 (Testolone): A Selective Androgen Receptor Modulator for Laboratory Research Use Only

Abstract

RAD-140, commonly known as Testolone, is a synthetic, nonsteroidal selective androgen receptor modulator (SARM) developed for experimental research involving androgen receptor signaling, muscle and bone biology, and tissue-selective anabolic activity. While RAD-140 exhibits strong androgen receptor affinity in preclinical studies, there is no reliable scientific evidence confirming its safety or efficacy for human performance enhancement or medical treatment. Its use is restricted exclusively to laboratory and research settings.

Chemical and Pharmacological Overview

RAD-140 is classified as a next-generation SARM, engineered to selectively activate androgen receptors in skeletal muscle and bone tissue while limiting activity in androgen-sensitive organs such as the prostate and sebaceous glands.

Its nonsteroidal structure differentiates RAD-140 from traditional anabolic steroids, making it a compound of interest in laboratory research focused on androgen selectivity, anabolic signaling, and receptor-mediated gene transcription.

Key Characteristics

  • Compound Name: RAD-140
  • Common Name: Testolone
  • Chemical Class: Nonsteroidal Selective Androgen Receptor Modulator (SARM)
  • Primary Target: Androgen receptor (AR)
  • Intended Use: Laboratory research only

Mechanism of Action (Research Context)

RAD-140 binds with high affinity to androgen receptors within target cells. Upon receptor binding, the RAD-140–AR complex translocates to the nucleus, where it interacts with androgen response elements (AREs) on DNA. This interaction modulates transcription of genes associated with:

  • Muscle protein synthesis
  • Lean tissue preservation
  • Nitrogen retention
  • Bone mineralization pathways

Due to its pronounced receptor selectivity, RAD-140 is often studied in comparative anabolic-to-androgenic ratio models.

Research Applications

In controlled in vitro and preclinical research environments, RAD-140 has been investigated for:

  • Muscle wasting and cachexia models
  • Androgen receptor binding and signaling studies
  • Bone density and skeletal integrity research
  • Neuroprotective signaling pathway exploration
  • Structure–activity relationship (SAR) analysis of SARMs

⚠️ Important: Data derived from laboratory and animal models cannot be extrapolated to human use.

Safety and Toxicological Considerations

The long-term safety profile of RAD-140 in humans has not been established. Experimental observations raise potential concerns related to:

  • Suppression of endogenous androgen production
  • Alterations in lipid metabolism
  • Liver enzyme elevation
  • Endocrine system disruption with prolonged exposure

RAD-140 should only be handled by trained personnel using appropriate laboratory safety equipment and protocols.

Regulatory and Legal Status

  • United States:
    SARMs, including RAD-140, are illegal for inclusion in dietary supplements. Products marketed for human consumption containing RAD-140 may violate federal regulations.
  • Anti-Doping Regulations:
    RAD-140 is prohibited by:

    • World Anti-Doping Agency (WADA)
    • National Collegiate Athletic Association (NCAA)
  • Detection:
    RAD-140 and its metabolites are detectable in urine, making it incompatible with any drug-tested environment.

Ethical and Compliance Notice

RAD-140 (Testolone) is not approved for:

  • Human consumption
  • Veterinary use
  • Medical or therapeutic treatment
  • Nutritional supplementation

All experimental use must comply with institutional research standards, chemical handling regulations, and ethical guidelines.

RAD-140 (Testolone) remains a compound of significant scientific interest due to its potent and selective androgen receptor activity observed in laboratory studies. However, because of regulatory restrictions, incomplete human safety data, and anti-doping prohibitions, its application is strictly limited to laboratory research use only.

⚠️ Disclaimer

For laboratory research use only.
Not for human or animal consumption.
Not approved as a drug, supplement, or therapeutic agent.

Show

Filter

Tags

-
-
-

Start typing and press Enter to search

Shopping Cart

PEPTIDE SCINESES HNGKONG, The manufacturer of high purity 99% wholesale peptides, sarms,