Organic DSIP 10mg – HPLC 99% Purity | HPS

Name: Organic DSIP 10mg
SKU: HPS-Organic DSIP 10mg-1
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Organic DSIP 10mg from HPS is a high-purity research peptide containing 10 mg of Delta Sleep-Inducing Peptide (DSIP), a naturally occurring nonapeptide that has been investigated extensively in relation to sleep physiology, neuroendocrine signaling, stress responses, and circadian processes. HPS produces this research-grade DSIP with a stated HPLC purity of 99%, providing researchers with a defined peptide material suitable for controlled laboratory investigations.

DSIP is also known as Delta Sleep-Inducing Peptide, DSIP nonapeptide, and emideltide. Its documented peptide sequence is Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE). PubChem identifies DSIP as a nine-amino-acid peptide with a molecular formula of C₃₅H₄₈N₁₀O₁₅ and a molecular weight of approximately 848.8 g/mol. (PubChem)

Product Overview

Organic DSIP 10mg is designed for researchers studying peptide chemistry, neurobiology, sleep-related signaling, molecular physiology, and related experimental applications. The 10 mg presentation provides a practical quantity for laboratory workflows where accurate characterization, reproducibility, and analytical purity are important.

HPS emphasizes 99% HPLC purity for this DSIP product. High-performance liquid chromatography (HPLC) is widely used for peptide quality assessment because it can separate the principal peptide component from related impurities and degradation products. For research applications, analytical characterization is particularly important because peptide composition, purity, storage conditions, and handling can influence experimental outcomes.

Product Specification	Details
Product Name	Organic DSIP
Common Name	Delta Sleep-Inducing Peptide
Abbreviation	DSIP
Quantity	10 mg
Purity	99% HPLC
Manufacturer	HPS
Peptide Type	Nonapeptide
Sequence	WAGGDASGE
Molecular Formula	C₃₅H₄₈N₁₀O₁₅
Molecular Weight	848.8 g/mol
CAS Number	62568-57-4
Research Classification	Research use only

What Is DSIP?

Delta Sleep-Inducing Peptide, commonly abbreviated DSIP, is a small neuropeptide consisting of nine amino-acid residues. The sequence is:

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

or, using the standard one-letter amino-acid notation:

WAGGDASGE

This sequence and molecular characterization are independently catalogued by PubChem. (PubChem)

DSIP was identified because of its relationship to sleep-related physiological phenomena. Subsequent research has investigated the peptide in several biological contexts, including sleep architecture, electrophysiological activity, neurotransmitter systems, endocrine signaling, circadian patterns, and stress-related responses. PubChem describes DSIP as a peptide found in neurons, peripheral organs, and plasma and notes its reported effects across several neurophysiological systems. (PubChem)

Because DSIP is a relatively small peptide, it is also useful as a research subject for investigations involving peptide structure, sequence, stability, analytical characterization, and biological signaling.

DSIP and Sleep Research

The historical interest in DSIP is strongly connected with sleep research. The name “Delta Sleep-Inducing Peptide” reflects early observations concerning delta-frequency sleep activity.

Sleep is a complex physiological process involving multiple neural networks, neurotransmitter systems, hormones, circadian signals, and homeostatic mechanisms. Consequently, DSIP should not be regarded simply as a conventional sedative compound. Research has investigated whether DSIP can influence aspects of sleep organization and sleep-related physiological signaling rather than merely producing generalized sedation.

Experimental literature has explored DSIP in relation to sleep efficiency, sleep latency, delta-wave activity, and other aspects of sleep architecture. However, research findings should be interpreted carefully because studies have differed substantially in experimental design, administration route, populations, and endpoints.

For laboratory researchers, this makes DSIP particularly interesting as a model peptide for investigating the relationship between peptide signaling and sleep physiology.

Research Areas

Research involving DSIP has extended beyond sleep alone. Investigators have examined several potential biological areas.

Sleep Architecture

DSIP has historically been studied for its possible relationship with delta-wave and slow-wave sleep. Researchers can investigate changes in sleep architecture and electrophysiological parameters under controlled experimental conditions.

Neurophysiology

The peptide has been investigated in relation to neuronal activity and neurophysiological signaling. Its small size and defined sequence make it useful for controlled peptide research.

Neurotransmitter Research

Experimental work has examined relationships between DSIP and neurotransmitter systems. Such research can contribute to understanding how peptide signaling interacts with established neuronal pathways.

Circadian Biology

DSIP has also been studied in connection with circadian and locomotor patterns. This makes it relevant to research investigating biological timing and sleep-wake regulation.

Stress and Neuroendocrine Research

Researchers have investigated DSIP in relation to stress-associated and neuroendocrine processes. These areas are relevant to studies examining interactions between the nervous system, endocrine signaling, and physiological adaptation.

Peptide Chemistry

Beyond biological studies, DSIP can serve as a defined nonapeptide model for analytical chemistry. Its known sequence and molecular formula allow researchers to investigate peptide identity, purity, degradation, and analytical behavior.

Chemical Characteristics of DSIP

DSIP has a relatively compact molecular structure compared with larger peptides and proteins. It contains nine amino-acid residues and has a reported molecular weight of approximately 848.8 Da. PubChem lists its molecular formula as C₃₅H₄₈N₁₀O₁₅. (PubChem)

The presence of tryptophan at the N-terminal position is particularly relevant from an analytical perspective because aromatic amino acids can contribute to ultraviolet detection during chromatographic analysis.

The peptide also contains glycine, alanine, aspartic acid, serine, and glutamic acid residues. Its sequence therefore includes both neutral and acidic residues, contributing to the chemical properties of the complete peptide.

Chemical Structure Table

Chemical Parameter	DSIP Information
Chemical Name	Delta Sleep-Inducing Peptide
Alternative Name	Emideltide
Sequence	WAGGDASGE
Residue Count	9
Molecular Formula	C₃₅H₄₈N₁₀O₁₅
Molecular Weight	848.8 g/mol
CAS	62568-57-4
PubChem CID	68816
Peptide Class	Nonapeptide
N-Terminal Residue	Tryptophan
C-Terminal Residue	Glutamic acid
Primary Research Area	Sleep and neurobiology

The chemical identifiers and sequence above are consistent with PubChem’s current DSIP record. (PubChem)

HPLC 99% Purity

One of the principal specifications of Organic DSIP 10mg from HPS is its stated 99% HPLC purity.

HPLC, or high-performance liquid chromatography, is an important analytical technique for peptide characterization. It allows a sample to be separated into chromatographic components according to differences in chemical interaction with the stationary and mobile phases.

For peptide research, chromatographic purity is particularly valuable because synthesis can generate closely related species, truncated sequences, protecting-group remnants, oxidation products, or other process-related impurities.

A reported 99% HPLC purity indicates that the principal chromatographic component represents approximately 99% of the measured chromatographic area under the stated analytical conditions. Researchers should distinguish this analytical purity measurement from other characteristics such as peptide identity, water content, residual solvents, counterions, sterility, or endotoxin levels.

Therefore, an HPLC purity specification should be interpreted as an analytical purity measurement, not as a guarantee of suitability for human or veterinary administration.

Technical Specification

Technical Parameter	Specification
Material	DSIP peptide
Product Size	10 mg
Purity	≥99% HPLC*
Sequence	WAGGDASGE
Molecular Weight	848.8 g/mol
Peptide Length	9 amino acids
Appearance	Research-grade peptide material
Analytical Method	HPLC
Manufacturer	HPS
Intended Application	Laboratory research
Storage	Follow product-specific storage documentation
Use Classification	Research use only

*Based on the stated HPS product specification. Analytical results can depend on the testing method and conditions.

Why Choose HPS Organic DSIP?

HPS focuses on providing research peptides with defined specifications and analytical quality parameters. For researchers, a consistent material specification can be important when conducting experiments across multiple batches.

The Organic DSIP 10mg format offers several practical characteristics:

10 mg research quantity
99% HPLC purity specification
Defined WAGGDASGE sequence
Well-characterized molecular formula
Approximately 848.8 Da molecular weight
Suitable for peptide chemistry and laboratory research
Manufactured by HPS
Clear research-use positioning

A defined peptide sequence and analytical purity specification can help laboratories establish reproducible experimental conditions.

DSIP in Peptide Research

Peptide research increasingly examines short signaling molecules as tools for understanding biological processes. DSIP is particularly interesting because it represents a very small peptide with a defined nine-residue sequence but a history of investigation spanning multiple physiological systems.

Researchers may use DSIP as a model compound when investigating questions involving peptide stability, analytical separation, biological signaling, or interactions between neuropeptides and physiological systems.

Because the peptide contains only nine residues, it also provides a useful example for studying how relatively small structural changes can potentially influence peptide properties. Related DSIP analogues and structural variants have been investigated, demonstrating the importance of sequence and stereochemical configuration in peptide research. PubChem, for example, separately catalogs an isoaspartyl DSIP variant. (PubChem)

Quality and Analytical Considerations

When evaluating a research peptide, HPLC purity is only one component of overall quality assessment. Researchers should consider several analytical parameters.

Identity testing can help establish that the material corresponds to the intended peptide sequence.

HPLC analysis provides information about chromatographic purity and can identify major related components.

Mass spectrometry can provide molecular-mass information useful for confirming peptide identity.

Water-content testing may be relevant because lyophilized peptides can contain variable amounts of residual moisture.

Storage stability is also important because peptides can undergo degradation under inappropriate environmental conditions.

For serious laboratory applications, researchers should consult the applicable Certificate of Analysis (COA) and product documentation rather than relying solely on a general product description.

Research-Only Positioning

Organic DSIP 10mg is intended for laboratory research and analytical purposes only. It is not presented as a dietary supplement, approved medicine, or treatment for insomnia, sleep disorders, anxiety, depression, or other medical conditions.

Although DSIP has been investigated in humans and experimental models, historical research does not establish that commercially supplied DSIP is an approved treatment. Researchers should distinguish experimental findings from established clinical indications.

The product should therefore be handled by appropriately qualified personnel in accordance with applicable institutional, laboratory, and regulatory requirements.

Handling and Storage

Peptides can be sensitive to environmental conditions. Exposure to excessive heat, moisture, repeated temperature cycling, or inappropriate solvents may affect peptide integrity.

For research use, laboratories should follow the storage and handling conditions supplied with the specific HPS batch. Researchers should also minimize unnecessary exposure to environmental conditions during sample preparation.

A controlled laboratory workflow should include appropriate labeling, documented storage conditions, batch identification, and analytical records.

Frequently Asked Questions

What is Organic DSIP 10mg?

Organic DSIP 10mg is a research-grade preparation of Delta Sleep-Inducing Peptide supplied in a 10 mg quantity by HPS. The product is specified at 99% HPLC purity.

What does DSIP stand for?

DSIP stands for Delta Sleep-Inducing Peptide. It is also known as DSIP nonapeptide and emideltide.

What is the DSIP sequence?

The DSIP sequence is WAGGDASGE, corresponding to Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. (PubChem)

What is the molecular weight of DSIP?

PubChem lists the molecular weight of DSIP as approximately 848.8 g/mol. (PubChem)

What is the molecular formula?

The molecular formula is C₃₅H₄₈N₁₀O₁₅. (PubChem)

What does 99% HPLC purity mean?

It means the principal chromatographic component accounts for approximately 99% of the measured chromatographic area under the specified HPLC method. It should not be interpreted as a guarantee of sterility, endotoxin-free status, or clinical suitability.

Is DSIP a sleep medication?

No. DSIP is an experimental peptide that has been investigated in sleep-related research. This research product is not represented as an approved sleep medication.

Who manufactures this DSIP?

The product described here is manufactured by HPS, with a stated HPLC purity of 99%.

What is the quantity?

Each product contains 10 mg of DSIP.

Can DSIP be used for human treatment?

This product is designated for research use only and should not be used as a human therapeutic product. Researchers should follow applicable institutional and regulatory requirements.

Conclusion

Organic DSIP 10mg from HPS provides researchers with a defined Delta Sleep-Inducing Peptide preparation featuring a WAGGDASGE sequence and a stated 99% HPLC purity. DSIP is a nine-amino-acid neuropeptide that has attracted scientific interest because of its historical association with delta-wave sleep and its broader investigation in neurophysiology, neurotransmitter regulation, circadian biology, stress-related processes, and neuroendocrine research.

Its well-defined chemical structure, relatively small molecular size, and established research history make DSIP a useful compound for laboratory investigation. PubChem identifies the compound as a nonapeptide with the molecular formula C₃₅H₄₈N₁₀O₁₅, molecular weight approximately 848.8 g/mol, and CAS number 62568-57-4. (PubChem)

For laboratories seeking a high-purity research material, the HPS specification of 99% HPLC purity provides an important analytical benchmark. As with any research peptide, however, purity should be evaluated together with identity confirmation, batch-specific analytical documentation, storage conditions, and the requirements of the intended experimental protocol.

Organic DSIP 10mg – HPLC 99% purity, manufactured by HPS – is intended strictly for research and laboratory use.

DOWNLOAD OF COA- DSIP

DSIP Chemical Specification Table

Chemical Parameter	DSIP Specification
Product Name	Organic DSIP
Full Name	Delta Sleep-Inducing Peptide
Alternative Name	Emideltide
Abbreviation	DSIP
Peptide Type	Nonapeptide
Amino Acid Sequence	Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
One-Letter Sequence	WAGGDASGE
Molecular Formula	C₃₅H₄₈N₁₀O₁₅
Molecular Weight	848.8 g/mol
CAS Number	62568-57-4
PubChem CID	68816
Number of Amino Acids	9
N-Terminal Residue	Tryptophan (Trp/W)
C-Terminal Residue	Glutamic Acid (Glu/E)
Peptide Class	Short neuropeptide
Research Category	Peptide / Neurobiology Research
Purity	99% HPLC

Key Product Data

Specification	Value
DSIP Quantity	10 mg
Purity	99% HPLC
Sequence	WAGGDASGE
Molecular Formula	C₃₅H₄₈N₁₀O₁₅
Molecular Weight	848.8 g/mol
CAS	62568-57-4
Manufacturer	HPS
Product Classification	Research Use Only

DSIP Technical Specification Table

Technical Parameter	Specification
Product	Organic DSIP 10mg
Manufacturer	HPS
Net Peptide Content	10 mg
HPLC Purity	99%
Material Type	Research-grade peptide
Peptide Length	9 amino acids
Molecular Weight	~848.8 Da
Sequence	WAGGDASGE
Analytical Method	HPLC
Identity Confirmation	Batch-specific analytical documentation
Physical Form	Peptide material supplied according to HPS batch specification
Packaging	Research-use packaging
Batch Identification	Batch/lot specific
COA	Available according to product documentation
Intended Application	Laboratory and analytical research
Research Fields	Peptide chemistry, neurobiology, sleep research, molecular physiology
Storage	Follow HPS batch-specific storage instructions
Handling	Handle according to laboratory peptide-handling procedures
Intended Use	Research Use Only
Human/Veterinary Use	Not intended for human or veterinary administration

DSIP Amino Acid Composition

Position	Amino Acid	1-Letter Code	3-Letter Code
1	Tryptophan	W	Trp
2	Alanine	A	Ala
3	Glycine	G	Gly
4	Glycine	G	Gly
5	Aspartic Acid	D	Asp
6	Alanine	A	Ala
7	Serine	S	Ser
8	Glycine	G	Gly
9	Glutamic Acid	E	Glu

ENGLISH

DSIP (Delta Sleep-Inducing Peptide) – High-Purity Laboratory Peptide (≥99% HPLC) – Manufactured by HPS

Product Overview

Product Name: DSIP (Delta Sleep-Inducing Peptide)
CAS Number: 62568-57-4
Molecular Formula: C35H48N10O15
Molecular Weight: 848.81 g/mol
Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Synonyms: Delta Sleep-Inducing Peptide, DSIP peptide
Manufacturer: HPS (High Purity Science)
Purity: ≥99% (Verified by High-Performance Liquid Chromatography – HPLC)
Form: Lyophilized white powder
Packaging: Pharmaceutical-grade research vial
Intended Use: For laboratory research only, not for human or veterinary use

Introduction to DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide first isolated from the brains of rabbits in 1977. It has been extensively studied for its role in sleep regulation, modulation of biological rhythms, and neuroendocrine regulation. Its structure consists of nine amino acids, making it a nonapeptide with notable neuromodulatory and regulatory properties.

This synthetic version of DSIP, produced by HPS (High Purity Science), is manufactured under rigorous laboratory conditions, ensuring ≥99% purity confirmed by HPLC analysis. It is formulated specifically for scientific research, allowing researchers to explore its physiological, biochemical, and neurobiological effects with high reproducibility and reliability.

Key Features

High Purity: ≥99% confirmed by HPLC
Pharmaceutical-grade lyophilization for long-term stability
Reliable sourcing from HPS, a reputed manufacturer of research-grade peptides
Strict quality assurance and batch traceability
Intended solely for in vitro and preclinical laboratory research

Biological Significance

DSIP plays a crucial role in several physiological and neurological processes:

1. Sleep Regulation

The peptide was originally identified for its sleep-promoting effects, particularly its ability to induce slow-wave sleep (SWS) without affecting rapid eye movement (REM) phases. Research has shown that DSIP may modulate the release of neurotransmitters involved in sleep architecture, including serotonin and norepinephrine.

2. Endocrine Regulation

DSIP appears to influence the secretion of several hormones, such as:

Corticotropin (ACTH)
Luteinizing hormone (LH)
Growth hormone (GH)

Studies have suggested its involvement in hypothalamic-pituitary axis regulation.

3. Stress Modulation

DSIP has been observed to reduce corticosterone levels, suggesting a role in stress mitigation and anti-anxiety behavior in animal models. This effect may relate to its modulation of the GABAergic and serotonergic systems.

4. Pain Perception

Research has also explored DSIP’s influence on analgesia. It may have a modulatory effect on opioid receptor systems, potentially enhancing or reducing pain thresholds under certain conditions.

5. Thermoregulation and Circadian Rhythms

DSIP is believed to affect thermoregulation, body temperature, and biological rhythms, making it a subject of interest in chronobiology and chronotherapy.

Research Applications

Because of its broad physiological influence, DSIP is studied in various research areas:

Research Area	Focus
Neuroscience	Sleep cycles, neurotransmission, pain modulation
Endocrinology	Hormonal balance, growth hormone modulation
Psychopharmacology	Stress, anxiety, depression models
Chronobiology	Circadian rhythm, biological clock studies
Immunology	Interaction with immune responses and cytokine regulation
Metabolic Research	Potential link to metabolic rate and energy homeostasis

Manufacturing and Quality Control by HPS

HPS (High Purity Science) follows stringent Good Manufacturing Practices (GMP) for peptide synthesis. All batches of DSIP are produced under sterile, temperature-controlled conditions using solid-phase peptide synthesis (SPPS). The peptide undergoes several purification stages and is verified for ≥99% purity using High-Performance Liquid Chromatography (HPLC).

Quality Parameters:

Purity (HPLC): ≥99%
Endotoxin Level: <0.1 EU/mg
Moisture Content: <6%
Solubility: Soluble in water, dilute acetic acid, or DMSO
Appearance: White, lyophilized powder
Storage Temperature: -20°C for long-term storage

All products include a Certificate of Analysis (COA) for quality verification, batch number tracking, and expiration date.

HPLC Analysis (Summary)

Each batch of DSIP is analyzed via HPLC to ensure the consistency of peptide chain, purity, and absence of degradation or contamination. Here’s a typical HPLC profile summary (available in the accompanying COA file):

Parameter	Value
Retention Time	5.24 minutes
Peak Purity	≥99.03%
Impurities Detected	<0.5% total (no major peaks)
Detection Wavelength	220 nm

This profile ensures research reliability and replicability.

Reconstitution & Storage Guidelines

Reconstitution:

DSIP should be reconstituted in sterile distilled water, 0.9% saline, or buffered solution (e.g., PBS) before use in research. Concentration should be adjusted based on experimental design.

Storage:

Lyophilized Form: Stable at -20°C for ≥24 months.
After Reconstitution: Store at 2-8°C and use within 7–14 days.
Avoid repeated freeze-thaw cycles to preserve peptide structure.

Packaging Options

HPS provides DSIP in:

1 mg vial
2 mg vial
5 mg vial
Custom bulk orders available upon request

All vials are sealed in light-resistant, nitrogen-flushed containers, vacuum packed to preserve stability and purity.

Legal and Safety Disclaimer

This product is strictly intended for laboratory and scientific research. It is not approved for diagnostic, therapeutic, or human consumption purposes. Misuse of DSIP outside of approved research protocols may be subject to legal penalties.

Personal Protective Equipment (PPE) should be used when handling DSIP in any form, including gloves, lab coats, and eye protection. Use within a certified laboratory environment under guidance from qualified personnel.

Why Choose HPS for Peptides?

HPS (High Purity Science) is a trusted name in peptide production, with a focus on purity, quality assurance, and consistency across all batches. Researchers around the globe rely on HPS for their:

ISO 9001:2015 certified manufacturing protocols
Full-spectrum analytical documentation (COA, HPLC, MS)
Transparent sourcing and technical support
Custom peptide development services

With HPS, researchers can expect reproducibility, batch integrity, and competitive pricing—making it a preferred source for academic institutions, biotech firms, and pharmacological labs.

Conclusion

DSIP (Delta Sleep-Inducing Peptide) represents a unique area of research within neurobiology, endocrinology, and sleep science. Manufactured by HPS with ≥99% HPLC purity, it ensures reliable performance in various preclinical research models.

By adhering to rigorous quality standards, HPS offers DSIP that is trusted, pure, and reproducible—backed with full analytical documentation and research-grade packaging.

DEUTSCH

DSIP (Delta Sleep-Inducing Peptide) – Hochreines Laborpeptid (≥99 % HPLC) – Hergestellt von HPS

Produktübersicht

Produktname: DSIP (Delta Sleep-Inducing Peptide)
CAS-Nummer: 62568-57-4
Molekularformel: C₃₅H₄₈N₁₀O₁₅
Molekulargewicht: 848.81 g/mol
Sequenz: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Synonyme: Delta Sleep-Inducing Peptid, DSIP-Peptid
Hersteller: HPS (High Purity Science)
Reinheit: ≥99 % (bestätigt durch Hochleistungsflüssigkeitschromatographie – HPLC)
Form: Lyophilisiertes weißes Pulver
Verpackung: Forschungsfläschchen in pharmazeutischer Qualität
Verwendungszweck: Nur für wissenschaftliche Forschung. Nicht zur Anwendung am Menschen oder Tier bestimmt.

Einführung in DSIP

DSIP (Delta Sleep-Inducing Peptide) ist ein natürlich vorkommendes Neuropeptid, das erstmals 1977 aus den Gehirnen von Kaninchen isoliert wurde. Es wurde umfangreich im Hinblick auf seine Rolle bei der Schlafregulation, der Modulation biologischer Rhythmen und der neuroendokrinen Steuerung untersucht. Die Struktur besteht aus neun Aminosäuren und macht DSIP zu einem Nonapeptid mit bemerkenswerten neuromodulatorischen und regulatorischen Eigenschaften.

Die synthetische Version von DSIP, hergestellt von HPS (High Purity Science), wird unter strengen Laborbedingungen produziert, mit einer garantierten Reinheit von ≥99 %, bestätigt durch HPLC. Diese Formulierung ist speziell für wissenschaftliche Studien entwickelt worden, um Forscher*innen eine verlässliche Grundlage für physiologische, biochemische und neurobiologische Experimente zu bieten.

Hauptmerkmale

Hochreine Qualität: ≥99 % Reinheit durch HPLC bestätigt
Pharmazeutisch gefriergetrocknet zur langfristigen Stabilität
Vertrauenswürdiger Hersteller (HPS) mit hoher Produktionskompetenz
Strenge Qualitätskontrollen und Rückverfolgbarkeit jeder Charge
Ausschließlich für In-vitro- und vorklinische Forschungszwecke

Biologische Bedeutung von DSIP

1. Schlafregulation:
DSIP wurde ursprünglich wegen seiner schlaffördernden Wirkung entdeckt, insbesondere durch die Fähigkeit, den Tiefschlaf (Slow-Wave Sleep, SWS) zu induzieren, ohne die REM-Phasen zu beeinträchtigen. Es moduliert die Ausschüttung schlafrelevanter Neurotransmitter wie Serotonin und Noradrenalin.

2. Endokrine Regulation:
DSIP beeinflusst die Sekretion mehrerer Hormone, darunter:

Corticotropin (ACTH)
Luteinisierendes Hormon (LH)
Wachstumshormon (GH)
Diese Effekte stehen im Zusammenhang mit der Hypothalamus-Hypophysen-Achse.

3. Stressmodulation:
In Tiermodellen reduziert DSIP die Corticosteronspiegel und zeigt anxiolytische (angstlösende) Eigenschaften, wahrscheinlich über die GABAergen und serotonergen Systeme.

4. Schmerzwahrnehmung:
DSIP beeinflusst möglicherweise das Schmerzempfinden durch seine Wechselwirkungen mit Opioidrezeptoren.

5. Thermoregulation und zirkadiane Rhythmen:
DSIP scheint Körpertemperatur und biologische Rhythmen zu beeinflussen, was es zu einem interessanten Forschungsobjekt in der Chronobiologie macht.

Forschungsanwendungen

Forschungsfeld	Fokus
Neurowissenschaften	Schlafzyklen, Neurotransmission, Schmerzmodulation
Endokrinologie	Hormonhaushalt, Wachstumshormonaktivität
Psychopharmakologie	Stress, Angst, Depression
Chronobiologie	Zirkadiane Rhythmen, biologische Uhren
Immunologie	Einfluss auf Immunantworten und Zytokinregulation
Stoffwechselforschung	Zusammenhang mit Energiehaushalt und Stoffwechselrate

Herstellung & Qualitätskontrolle durch HPS

HPS (High Purity Science) wendet strenge GMP-Richtlinien (Good Manufacturing Practice) bei der Peptidsynthese an. DSIP wird durch Festphasenpeptidsynthese (SPPS) unter sterilen Bedingungen hergestellt, mehrfach gereinigt und auf Reinheit von ≥99 % per HPLC getestet.

Qualitätsparameter:

HPLC-Reinheit: ≥99 %
Endotoxingehalt: <0,1 EU/mg
Feuchtigkeitsgehalt: <6 %
Löslichkeit: In Wasser, verdünnter Essigsäure oder DMSO löslich
Erscheinungsbild: Weißes lyophilisiertes Pulver
Lagerung: -20 °C für Langzeitlagerung empfohlen

Jede Charge wird mit einem Analysezertifikat (COA) ausgeliefert, inklusive Chargennummer, Verfallsdatum und HPLC-Daten.

HPLC-Analyse (Zusammenfassung)

Jede Charge DSIP wird mittels HPLC auf Konsistenz, Reinheit und eventuelle Verunreinigungen geprüft. Beispielprofil:

Parameter	Wert
Retentionszeit	5,24 Minuten
Peak-Reinheit	≥99,03 %
Gesamtverunreinigungen	<0,5 %
Detektionswellenlänge	220 nm

Dieses Profil sichert Reproduzierbarkeit und Validität für wissenschaftliche Studien.

Rekonstitution & Lagerung

Rekonstitution:
DSIP sollte in sterilem Wasser, 0,9 % Kochsalzlösung oder einem geeigneten Puffer (z. B. PBS) gelöst werden. Die Konzentration richtet sich nach dem Versuchsprotokoll.

Lagerung:

Lyophilisierte Form: Stabil bei -20 °C für mindestens 24 Monate
Nach Rekonstitution: 2–8 °C, innerhalb von 7–14 Tagen verbrauchen
Hinweis: Wiederholtes Einfrieren und Auftauen vermeiden

Verpackungsoptionen

Verfügbar in den folgenden Mengen:

1 mg Vial
2 mg Vial
5 mg Vial
Individuelle Großbestellungen auf Anfrage möglich

Alle Vials werden lichtgeschützt, vakuumversiegelt und unter Stickstoffatmosphäre geliefert.

Rechtlicher Hinweis & Sicherheit

Dieses Produkt ist ausschließlich für wissenschaftliche Laborforschung vorgesehen. Es ist nicht für diagnostische oder therapeutische Anwendungen beim Menschen oder Tier zugelassen. Jeglicher Missbrauch kann rechtliche Konsequenzen nach sich ziehen.

Sicherheitsausrüstung (PSA) wie Laborkittel, Handschuhe und Schutzbrille ist beim Umgang mit DSIP erforderlich. Nur in zugelassenen Laboren unter Aufsicht qualifizierter Fachkräfte verwenden.

Warum DSIP von HPS wählen?

HPS (High Purity Science) ist bekannt für:

ISO 9001:2015-zertifizierte Herstellungsverfahren
Vollständige analytische Dokumentation (COA, HPLC, MS)
Transparente Lieferketten & technischen Support
Maßgeschneiderte Peptidsynthese für Forschungseinrichtungen

Forschende weltweit vertrauen auf HPS wegen der hohen Qualität, gleichbleibenden Reinheit und zuverlässigen Lieferung.

Fazit

DSIP (Delta Sleep-Inducing Peptide) stellt ein faszinierendes Forschungsfeld dar – insbesondere in den Bereichen Neurobiologie, Endokrinologie und Schlafwissenschaften. Die von HPS hergestellte Version mit ≥99 % HPLC-geprüfter Reinheit garantiert zuverlässige Resultate in vorklinischen Studien.

Dank rigoroser Qualitätskontrollen, transparenter Analytik und forschungsgerechter Verpackung ist DSIP von HPS eine exzellente Wahl für moderne Labore und akademische Institutionen.

français

DSIP (Peptide Inducteur du Sommeil Delta) – Peptide de Recherche de Haute Pureté (≥99 % HPLC) – Fabriqué par HPS

Présentation du Produit

Nom du produit : DSIP (Peptide Inducteur du Sommeil Delta)
Numéro CAS : 62568-57-4
Formule moléculaire : C₃₅H₄₈N₁₀O₁₅
Masse moléculaire : 848,81 g/mol
Séquence : Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Synonymes : Peptide inducteur du sommeil delta, peptide DSIP
Fabricant : HPS (High Purity Science)
Pureté : ≥99 % (vérifiée par chromatographie liquide haute performance – HPLC)
Forme : Poudre blanche lyophilisée
Conditionnement : Flacon de qualité pharmaceutique pour recherche
Utilisation prévue : À usage exclusivement en recherche scientifique, non destiné à un usage humain ou vétérinaire

Introduction au DSIP

Le DSIP (Delta Sleep-Inducing Peptide) est un neuropeptide naturellement présent, isolé pour la première fois dans les années 1970 à partir du cerveau de lapins. Il est reconnu pour son rôle dans la régulation du sommeil, les rythmes biologiques et l’équilibre neuroendocrinien. Composé de neuf acides aminés, c’est un nonapeptide possédant des propriétés neuromodulatrices remarquables.

La version synthétique de DSIP produite par HPS (High Purity Science) est élaborée selon des conditions de laboratoire strictes, assurant une pureté ≥99 %, confirmée par analyse HPLC. Elle est spécialement conçue pour les laboratoires de recherche souhaitant étudier ses effets physiologiques, biochimiques et neurologiques avec précision et fiabilité.

Caractéristiques Clés

Pureté exceptionnelle : ≥99 % vérifiée par HPLC
Lyophilisation de qualité pharmaceutique pour une meilleure stabilité
Fournisseur de confiance (HPS), spécialisé dans les peptides de laboratoire
Contrôle qualité strict avec traçabilité des lots
Réservé exclusivement à la recherche in vitro et préclinique

Importance Biologique du DSIP

1. Régulation du sommeil
Le DSIP est reconnu pour ses effets inducteurs du sommeil profond (sommeil à ondes lentes – SWS), sans perturber les phases REM. Il agirait en modulant les neurotransmetteurs impliqués dans l’architecture du sommeil, tels que la sérotonine et la noradrénaline.

2. Régulation endocrinienne
Le DSIP influence la sécrétion de plusieurs hormones :

Corticotrophine (ACTH)
Hormone lutéinisante (LH)
Hormone de croissance (GH)

Son action semble liée à l’axe hypothalamo-hypophysaire.

3. Modulation du stress
Chez les animaux, il réduit les taux de corticostérone, suggérant une activité anxiolytique et anti-stress, probablement via les systèmes GABAergique et sérotoninergique.

4. Perception de la douleur
Des études suggèrent que le DSIP pourrait avoir un effet modulateur sur les récepteurs opioïdes, influençant la sensibilité à la douleur.

5. Thermorégulation et rythmes circadiens
Le DSIP est également impliqué dans la régulation de la température corporelle et des rythmes biologiques, ce qui en fait un sujet d’intérêt en chronobiologie.

Applications en Recherche

Domaine de recherche	Objet d’étude
Neurosciences	Sommeil, neurotransmission, modulation de la douleur
Endocrinologie	Sécrétion hormonale, axe H-H, hormone de croissance
Psychopharmacologie	Stress, anxiété, dépression
Chronobiologie	Rythmes biologiques, sommeil et horloge interne
Immunologie	Réponse immunitaire, régulation des cytokines
Recherche métabolique	Taux métabolique, énergie et homéostasie

Fabrication & Contrôle Qualité par HPS

HPS (High Purity Science) applique des Bonnes Pratiques de Fabrication (GMP) strictes pour la synthèse de peptides. Le DSIP est fabriqué par synthèse peptidique en phase solide (SPPS) dans des conditions stériles, contrôlées en température. Chaque lot est purifié et analysé via HPLC pour garantir une pureté de ≥99 %.

Paramètres de qualité :

Pureté (HPLC) : ≥99 %
Endotoxines : <0,1 EU/mg
Teneur en eau : <6 %
Solubilité : Soluble dans l’eau, l’acide acétique dilué ou le DMSO
Aspect : Poudre blanche lyophilisée
Conservation : -20 °C pour stockage longue durée

Un certificat d’analyse (COA) est fourni avec chaque lot, incluant le numéro de lot, la date de péremption et les données HPLC.

Analyse HPLC (Résumé)

Chaque lot est contrôlé par HPLC pour vérifier l’intégrité de la chaîne peptidique, la pureté, et l’absence d’impuretés ou de dégradation.

Paramètre	Valeur
Temps de rétention	5,24 minutes
Pureté du pic	≥99,03 %
Impuretés détectées	<0,5 %
Longueur d’onde de détection	220 nm

Ces résultats garantissent des conditions optimales pour des recherches reproductibles.

Instructions de Reconstitution & Stockage

Reconstitution :
Dissoudre le DSIP dans de l’eau stérile, une solution saline à 0,9 % ou un tampon approprié (ex. PBS). La concentration doit être adaptée au protocole expérimental.

Stockage :

Poudre lyophilisée : Stable à -20 °C pendant ≥24 mois
Après reconstitution : Conserver entre 2–8 °C, à utiliser dans un délai de 7–14 jours
Important : Éviter les cycles répétés de congélation/décongélation

Options de Conditionnement

Disponible en flacons de :

1 mg
2 mg
5 mg
Commandes en vrac personnalisées sur demande

Les flacons sont scellés sous atmosphère d’azote, protégés de la lumière, et conditionnés sous vide pour préserver la stabilité.

Avis Légal & Sécurité

Ce produit est strictement réservé à la recherche scientifique. Il n’est pas destiné à un usage médical ou vétérinaire, ni à la consommation humaine. Toute utilisation hors cadre réglementé peut entraîner des sanctions.

Équipement de protection individuelle (EPI) obligatoire : gants, blouse de laboratoire et lunettes de sécurité. Utiliser uniquement en environnement de laboratoire certifié, sous supervision professionnelle.

Pourquoi Choisir les Peptides de HPS ?

HPS (High Purity Science) est reconnu pour :

Son protocole de fabrication certifié ISO 9001:2015
Une documentation analytique complète (COA, HPLC, spectrométrie de masse)
Une traçabilité totale et un support technique réactif
Des services personnalisés pour le développement de peptides sur mesure

Les laboratoires académiques, cliniques et pharmaceutiques du monde entier font confiance à HPS pour leur engagement en matière de qualité, de reproductibilité et de transparence.

Conclusion

Le DSIP (Peptide Inducteur du Sommeil Delta) est un outil de recherche prometteur en neurobiologie, endocrinologie et sciences du sommeil. Fabriqué par HPS avec une pureté ≥99 %, il offre une fiabilité exceptionnelle pour des modèles expérimentaux précliniques.

Grâce à ses normes de qualité rigoureuses, sa documentation analytique complète et son conditionnement professionnel, le DSIP d’HPS est un choix de confiance pour toute équipe de recherche scientifique.

español

DSIP (Péptido Inductor del Sueño Delta) – Péptido de Investigación de Alta Pureza (≥99 % HPLC) – Fabricado por HPS

Resumen del Producto

Nombre del producto: DSIP (Delta Sleep-Inducing Peptide)
Número CAS: 62568-57-4
Fórmula molecular: C₃₅H₄₈N₁₀O₁₅
Peso molecular: 848.81 g/mol
Secuencia: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Sinónimos: Péptido inductor del sueño delta, péptido DSIP
Fabricante: HPS (High Purity Science)
Pureza: ≥99 % (verificada por cromatografía líquida de alta resolución – HPLC)
Forma: Polvo blanco liofilizado
Envase: Vial de calidad farmacéutica para investigación
Uso previsto: Solo para investigación científica, no para uso humano ni veterinario

Introducción al DSIP

El DSIP (Péptido Inductor del Sueño Delta) es un neuropéptido natural identificado por primera vez en cerebros de conejos en 1977. Ha sido ampliamente estudiado por su papel en la regulación del sueño, los ritmos biológicos y el control neuroendocrino. Está compuesto por nueve aminoácidos, lo que lo convierte en un nonapéptido con propiedades neuromoduladoras y reguladoras notables.

La versión sintética de DSIP, producida por HPS, se fabrica bajo condiciones de laboratorio estrictas, garantizando una pureza ≥99 % confirmada por HPLC. Está formulado específicamente para estudios científicos que buscan explorar sus efectos fisiológicos, bioquímicos y neurológicos con gran confiabilidad y reproducibilidad.

Características Principales

Alta pureza: ≥99 % verificada por HPLC
Liofilización de calidad farmacéutica para mayor estabilidad
Proveedor confiable (HPS) especializado en péptidos de laboratorio
Control de calidad riguroso y trazabilidad por lote
Uso exclusivo para investigación in vitro y preclínica

Importancia Biológica del DSIP

1. Regulación del sueño
El DSIP fue identificado por su capacidad para inducir el sueño profundo (sueño de ondas lentas – SWS) sin alterar las fases REM. Se cree que modula neurotransmisores clave en la arquitectura del sueño, como la serotonina y la noradrenalina.

2. Regulación endocrina
El DSIP influye en la secreción de varias hormonas, entre ellas:

Corticotropina (ACTH)
Hormona luteinizante (LH)
Hormona del crecimiento (GH)
Se ha sugerido que participa en la regulación del eje hipotálamo-hipófisis.

3. Modulación del estrés
En modelos animales, el DSIP reduce los niveles de corticosterona, lo que indica un posible efecto ansiolítico y anti-estrés, probablemente a través de los sistemas GABAérgico y serotoninérgico.

4. Percepción del dolor
La investigación indica que el DSIP podría modular la sensibilidad al dolor a través de los receptores opioides.

5. Termorregulación y ritmos circadianos
También se ha implicado al DSIP en la regulación de la temperatura corporal y los ritmos biológicos, lo que lo convierte en un objeto de estudio relevante en cronobiología.

Aplicaciones en Investigación

Área de investigación	Foco de estudio
Neurociencia	Ciclos del sueño, neurotransmisión, dolor
Endocrinología	Balance hormonal, eje H-H, hormona del crecimiento
Psicofarmacología	Estrés, ansiedad, depresión
Cronobiología	Ritmos circadianos, reloj biológico
Inmunología	Respuestas inmunitarias, regulación de citoquinas
Investigación metabólica	Tasa metabólica, equilibrio energético

Fabricación y Control de Calidad por HPS

HPS (High Purity Science) emplea estrictas Buenas Prácticas de Manufactura (GMP) en la síntesis de péptidos. El DSIP es fabricado mediante síntesis de péptido en fase sólida (SPPS), en condiciones estériles y controladas. Cada lote es purificado y evaluado mediante HPLC, garantizando una pureza de ≥99 %.

Parámetros de calidad:

Pureza (HPLC): ≥99 %
Nivel de endotoxinas: <0.1 EU/mg
Contenido de humedad: <6 %
Solubilidad: Soluble en agua, ácido acético diluido o DMSO
Apariencia: Polvo blanco liofilizado
Almacenamiento: -20 °C para almacenamiento a largo plazo

Se proporciona un Certificado de Análisis (COA) con cada lote, con número de lote, fecha de caducidad y perfil HPLC.

Análisis HPLC (Resumen)

Cada lote de DSIP se analiza por HPLC para asegurar la integridad de la cadena peptídica, la pureza y la ausencia de impurezas.

Parámetro	Valor
Tiempo de retención	5,24 minutos
Pureza del pico	≥99,03 %
Impurezas detectadas	<0,5 %
Longitud de onda de detección	220 nm

Estos datos aseguran alta reproducibilidad y fiabilidad en investigación.

Reconstitución y Almacenamiento

Reconstitución:
Reconstituir en agua estéril, solución salina al 0,9 % o un tampón como PBS. La concentración depende del protocolo experimental.

Almacenamiento:

Forma liofilizada: Estable a -20 °C durante ≥24 meses
Tras reconstitución: Conservar entre 2–8 °C, usar en 7–14 días
Evitar ciclos repetidos de congelación y descongelación

Opciones de Presentación

Disponible en viales de:

1 mg
2 mg
5 mg
Pedidos a granel personalizados disponibles bajo solicitud

Todos los viales se sellan en atmósfera de nitrógeno, protegidos de la luz y empacados al vacío para preservar su estabilidad y pureza.

Aviso Legal y Seguridad

Este producto es exclusivamente para uso en investigación científica. No está aprobado para diagnóstico, tratamiento ni consumo humano o veterinario. El mal uso fuera de los protocolos de investigación puede estar sujeto a sanciones legales.

Equipo de protección personal (EPP) obligatorio: guantes, bata de laboratorio y protección ocular. Solo debe ser manipulado en laboratorios certificados y bajo supervisión de personal cualificado.

¿Por qué elegir los péptidos de HPS?

HPS (High Purity Science) es reconocido por:

Protocolos de fabricación certificados ISO 9001:2015
Documentación analítica completa (COA, HPLC, espectrometría de masas)
Transparencia en la cadena de suministro y soporte técnico especializado
Servicios de desarrollo personalizado de péptidos para investigación

Laboratorios académicos, farmacéuticos y biotecnológicos de todo el mundo confían en HPS por su pureza, reproducibilidad y compromiso con la calidad.

Conclusión

El DSIP (Péptido Inductor del Sueño Delta) es un péptido prometedor en los campos de la neurobiología, endocrinología y ciencia del sueño. Fabricado por HPS con una pureza de ≥99 %, proporciona resultados fiables en modelos preclínicos de investigación.

Gracias a sus altos estándares de calidad, documentación completa y presentación profesional, el DSIP de HPS es una opción de confianza para instituciones científicas en todo el mundo.

polski

DSIP (Delta Sleep-Inducing Peptide) – Wysokoczystościowy Peptyd Badawczy (≥99% HPLC) – Wyprodukowany przez HPS

Opis Produktu

Nazwa produktu: DSIP (Delta Sleep-Inducing Peptide)
Numer CAS: 62568-57-4
Wzór chemiczny: C₃₅H₄₈N₁₀O₁₅
Masa molowa: 848,81 g/mol
Sekwencja: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Synonimy: Delta Sleep-Inducing Peptide, peptyd DSIP
Producent: HPS (High Purity Science)
Czystość: ≥99% (potwierdzona przez wysokosprawną chromatografię cieczową – HPLC)
Forma: Liofilizowany biały proszek
Opakowanie: Fiolka badawcza klasy farmaceutycznej
Przeznaczenie: Wyłącznie do zastosowań laboratoryjnych; nie do użytku u ludzi ani zwierząt

Wprowadzenie do DSIP

DSIP (Delta Sleep-Inducing Peptide) to naturalnie występujący neuropeptyd po raz pierwszy wyizolowany z mózgów królików w 1977 roku. Od tego czasu był intensywnie badany pod kątem roli w regulacji snu, rytmów biologicznych oraz funkcji neuroendokrynnych. Składa się z dziewięciu aminokwasów, co czyni go nonapeptydem o istotnych właściwościach modulacyjnych.

Wersja syntetyczna DSIP produkowana przez HPS jest wytwarzana w rygorystycznych warunkach laboratoryjnych, z gwarantowaną czystością ≥99%, potwierdzoną analizą HPLC. Produkt ten został zaprojektowany specjalnie do badań naukowych, zapewniając wysoką powtarzalność i wiarygodność wyników.

Kluczowe Cechy

Wysoka czystość: ≥99%, potwierdzona przez HPLC
Liofilizacja klasy farmaceutycznej dla długiej trwałości
Zaufany producent – HPS, specjalizujący się w peptydach badawczych
Rygorystyczna kontrola jakości i pełna identyfikowalność partii
Przeznaczony wyłącznie do badań in vitro i przedklinicznych

Znaczenie Biologiczne DSIP

1. Regulacja snu
DSIP został pierwotnie odkryty ze względu na swoje właściwości wspomagające sen – szczególnie wpływ na fazę snu głębokiego (slow-wave sleep, SWS), bez zaburzania fazy REM. Peptyd ten może modulować neuroprzekaźniki, takie jak serotonina i noradrenalina.

2. Regulacja hormonalna
DSIP wpływa na wydzielanie kilku ważnych hormonów:

Kortykotropiny (ACTH)
Hormonu luteinizującego (LH)
Hormonu wzrostu (GH)
Może uczestniczyć w regulacji osi podwzgórze–przysadka.

3. Modulacja stresu
Badania na zwierzętach wykazały, że DSIP obniża poziom kortykosteronu, co sugeruje jego działanie przeciwlękowe i antystresowe – prawdopodobnie poprzez układ GABAergiczny i serotoninergiczny.

4. Percepcja bólu
DSIP może modulować układ receptorów opioidowych, wpływając na próg odczuwania bólu.

5. Termoregulacja i rytmy dobowe
DSIP bierze udział w regulacji temperatury ciała i rytmów okołodobowych, co czyni go interesującym obiektem badań w dziedzinie chronobiologii.

Zastosowania Badawcze

Dziedzina badań	Zakres badań
Neurobiologia	Cykl snu, neurotransmisja, modulacja bólu
Endokrynologia	Równowaga hormonalna, oś H-H, hormon wzrostu
Psychofarmakologia	Stres, lęk, depresja
Chronobiologia	Rytmy dobowe, zegar biologiczny
Immunologia	Reakcje immunologiczne, regulacja cytokin
Badania metaboliczne	Tempo metabolizmu, równowaga energetyczna

Produkcja i Kontrola Jakości przez HPS

HPS (High Purity Science) stosuje ścisłe zasady Dobrej Praktyki Wytwarzania (GMP) przy syntezie peptydów. DSIP jest produkowany metodą syntezy peptydowej w fazie stałej (SPPS) w warunkach sterylnych i kontrolowanych temperaturowo. Każda partia podlega oczyszczeniu i analizie metodą HPLC w celu zapewnienia czystości ≥99%.

Parametry jakościowe:

Czystość (HPLC): ≥99%
Poziom endotoksyn: <0,1 EU/mg
Zawartość wilgoci: <6%
Rozpuszczalność: Rozpuszczalny w wodzie, rozcieńczonym kwasie octowym lub DMSO
Wygląd: Biały, liofilizowany proszek
Temperatura przechowywania: –20 °C (długoterminowo)

Każdy produkt zawiera certyfikat analizy (COA), numer partii, datę ważności oraz profil HPLC.

Analiza HPLC (Podsumowanie)

Każda partia DSIP jest analizowana przez HPLC w celu potwierdzenia czystości łańcucha peptydowego i wykrycia ewentualnych zanieczyszczeń.

Parametr	Wartość
Czas retencji	5,24 minuty
Czystość piku	≥99,03%
Wykryte zanieczyszczenia	<0,5%
Długość fali detekcji	220 nm

Profil ten gwarantuje wiarygodność i powtarzalność badań.

Rekonstytucja i Przechowywanie

Rekonstytucja:
DSIP należy rozpuścić w wodzie destylowanej (sterylnej), 0,9% roztworze soli fizjologicznej lub buforze (np. PBS). Stężenie należy dostosować do projektu eksperymentu.

Przechowywanie:

Forma liofilizowana: Stabilna przez ≥24 miesiące w –20 °C
Po rekonstytucji: Przechowywać w temperaturze 2–8 °C i zużyć w ciągu 7–14 dni
Unikać cykli zamrażania i rozmrażania

Opcje Pakowania

Dostępne opakowania:

Fiolka 1 mg
Fiolka 2 mg
Fiolka 5 mg
Zamówienia hurtowe na życzenie

Fiolki są pakowane próżniowo, zabezpieczone przed światłem i wypełnione azotem dla zachowania maksymalnej stabilności.

Informacje Prawne i Bezpieczeństwo

Produkt przeznaczony wyłącznie do badań naukowych. Nie dopuszczony do stosowania u ludzi ani zwierząt. Wykorzystanie poza zatwierdzonymi protokołami badawczymi może prowadzić do konsekwencji prawnych.

Środki ochrony osobistej (PPE), takie jak rękawiczki, fartuch laboratoryjny i okulary ochronne, są wymagane podczas obsługi DSIP. Używać tylko w laboratorium pod nadzorem wykwalifikowanego personelu.

Dlaczego warto wybrać peptydy HPS?

HPS (High Purity Science) oferuje:

Certyfikowane procedury produkcji (ISO 9001:2015)
Kompletną dokumentację analityczną (COA, HPLC, MS)
Przejrzystość w łańcuchu dostaw i wsparcie techniczne
Usługi niestandardowej syntezy peptydów na zamówienie

HPS cieszy się zaufaniem laboratoriów naukowych, instytutów akademickich i firm biotechnologicznych na całym świecie dzięki najwyższej jakości i niezawodności.

Podsumowanie

DSIP (Delta Sleep-Inducing Peptide) to unikalny związek badawczy w dziedzinie neurobiologii, endokrynologii i nauk o śnie. Wersja produkowana przez HPS o czystości ≥99% HPLC zapewnia doskonałe właściwości badawcze w modelach przedklinicznych.

Dzięki rygorystycznym standardom jakości i pełnej dokumentacji analitycznej, DSIP od HPS jest idealnym wyborem dla laboratoriów poszukujących wiarygodnego źródła peptydów badawczych.

italiano

DSIP (Delta Sleep-Inducing Peptide) – Peptide da Laboratorio ad Alta Purezza (≥99% HPLC) – Prodotto da HPS

Panoramica del Prodotto

Nome del prodotto: DSIP (Delta Sleep-Inducing Peptide)
Numero CAS: 62568-57-4
Formula molecolare: C₃₅H₄₈N₁₀O₁₅
Peso molecolare: 848,81 g/mol
Sequenza: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Sinonimi: Peptide delta induttore del sonno, peptide DSIP
Produttore: HPS (High Purity Science)
Purezza: ≥99% (verificata tramite cromatografia liquida ad alte prestazioni – HPLC)
Forma: Polvere bianca liofilizzata
Confezione: Fiala da laboratorio di grado farmaceutico
Uso previsto: Solo per ricerca scientifica. Non per uso umano o veterinario.

Introduzione al DSIP

Il DSIP (Delta Sleep-Inducing Peptide) è un neuropeptide di origine naturale scoperto per la prima volta nel 1977 nel cervello dei conigli. È stato oggetto di numerosi studi per il suo ruolo nella regolazione del sonno, nei ritmi biologici e nel controllo neuroendocrino. La sua struttura comprende nove amminoacidi, rendendolo un nonapeptide con proprietà neuromodulatorie rilevanti.

La versione sintetica di DSIP prodotta da HPS viene realizzata in condizioni di laboratorio altamente controllate, garantendo una purezza ≥99%, confermata da analisi HPLC. È formulata specificamente per la ricerca scientifica e assicura risultati affidabili e ripetibili.

Caratteristiche Principali

Purezza elevata: ≥99% certificata tramite HPLC
Liofilizzazione di qualità farmaceutica per una conservazione prolungata
Fornitore affidabile: HPS, leader nei peptidi da laboratorio
Rigorosi controlli di qualità con tracciabilità del lotto
Esclusivamente per studi preclinici e ricerca in vitro

Importanza Biologica del DSIP

1. Regolazione del sonno
Il DSIP è noto per la sua capacità di promuovere il sonno a onde lente (SWS), senza alterare la fase REM. Interviene probabilmente nella modulazione dei neurotrasmettitori come serotonina e noradrenalina.

2. Regolazione ormonale
Influenza la secrezione di diversi ormoni:

Corticotropina (ACTH)
Ormone luteinizzante (LH)
Ormone della crescita (GH)

Ha un ruolo importante nell’asse ipotalamo-ipofisario.

3. Riduzione dello stress
Negli studi animali, il DSIP ha dimostrato di ridurre i livelli di corticosterone, suggerendo un effetto ansiolitico e antistress, probabilmente mediato dal sistema GABAergico e serotoninergico.

4. Percezione del dolore
Può modulare la soglia del dolore agendo sui recettori oppioidi.

5. Termoregolazione e ritmi circadiani
DSIP sembra influenzare la temperatura corporea e i ritmi biologici, rendendolo un oggetto di studio nella cronobiologia.

Applicazioni nella Ricerca

Settore di ricerca	Area di studio
Neuroscienze	Cicli del sonno, trasmissione sinaptica, dolore
Endocrinologia	Regolazione ormonale, ormone della crescita
Psicofarmacologia	Ansia, stress, depressione
Cronobiologia	Ritmi circadiani, orologio biologico
Immunologia	Risposta immunitaria, modulazione delle citochine
Metabolismo	Regolazione energetica, metabolismo

Produzione e Controllo Qualità da parte di HPS

HPS (High Purity Science) segue rigorosamente le Buone Pratiche di Fabbricazione (GMP) nella sintesi dei peptidi. Il DSIP è prodotto con metodo SPPS (Solid-Phase Peptide Synthesis) in ambienti sterili e controllati. Ogni lotto è purificato e analizzato mediante HPLC per garantire purezza ≥99%.

Parametri di qualità:

Purezza (HPLC): ≥99%
Endotossine: <0,1 EU/mg
Contenuto di umidità: <6%
Solubilità: Solubile in acqua, acido acetico diluito o DMSO
Aspetto: Polvere bianca liofilizzata
Temperatura di conservazione: –20°C (per conservazione a lungo termine)

Ogni lotto è accompagnato da un Certificato di Analisi (COA) con numero di lotto, data di scadenza e profilo HPLC.

Analisi HPLC (Sintesi)

Ogni lotto di DSIP viene sottoposto ad analisi HPLC per verificare la catena peptidica, la purezza e l’assenza di contaminazioni.

Parametro	Valore
Tempo di ritenzione	5,24 minuti
Purezza del picco	≥99,03%
Impurità rilevate	<0,5%
Lunghezza d’onda rilevata	220 nm

Questi dati assicurano l’affidabilità sperimentale e la ripetibilità dei risultati.

Istruzioni per la Ricostituzione e la Conservazione

Ricostituzione:
Il DSIP va ricostituito in acqua sterile, soluzione fisiologica allo 0,9% o tampone PBS. La concentrazione deve essere regolata in base al protocollo sperimentale.

Conservazione:

Forma liofilizzata: stabile a –20 °C per ≥24 mesi
Dopo ricostituzione: conservare a 2–8 °C e usare entro 7–14 giorni
Evitare cicli ripetuti di congelamento e scongelamento

Opzioni di Confezionamento

Disponibile nei seguenti formati:

Fiala da 1 mg
Fiala da 2 mg
Fiala da 5 mg
Formati personalizzati su richiesta

Le fiale sono sigillate in atmosfera di azoto, protette dalla luce e confezionate sottovuoto per garantire la stabilità del prodotto.

Avvertenze Legali e di Sicurezza

Questo prodotto è destinato esclusivamente all’uso in laboratorio. Non è approvato per l’uso diagnostico, terapeutico o per il consumo umano o animale. L’uso improprio può comportare responsabilità legali.

Dispositivi di protezione individuale (DPI) obbligatori: guanti, camice da laboratorio, occhiali protettivi. Da utilizzare solo in laboratori certificati sotto supervisione qualificata.

Perché Scegliere i Peptidi HPS?

HPS (High Purity Science) è un’azienda di fiducia grazie a:

Certificazioni ISO 9001:2015
Documentazione completa: COA, HPLC, MS
Trasparenza nei processi produttivi e supporto tecnico dedicato
Servizi su misura per lo sviluppo di peptidi personalizzati

HPS è la scelta preferita da università, aziende biotech e laboratori farmaceutici per l’affidabilità e la qualità costante dei suoi peptidi.

Conclusione

DSIP (Delta Sleep-Inducing Peptide) rappresenta un importante strumento di ricerca nei settori della neurobiologia, endocrinologia e scienza del sonno. La sua versione sintetica prodotta da HPS con purezza ≥99% HPLC offre risultati affidabili nei modelli preclinici.

Con il suo impegno nella qualità e nella trasparenza, HPS è il partner ideale per ricercatori che necessitano di peptidi puri, tracciabili e riproducibili.

Русский

DSIP (Дельта-сон-индуцирующий пептид) – Лабораторный пептид высокой чистоты (≥99% по HPLC) – Производитель: HPS

Общая информация о продукте

Название: DSIP (Delta Sleep-Inducing Peptide)
CAS-номер: 62568-57-4
Молекулярная формула: C₃₅H₄₈N₁₀O₁₅
Молекулярная масса: 848.81 г/моль
Аминокислотная последовательность: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Синонимы: Пептид, индуцирующий дельта-сон, DSIP
Производитель: HPS (High Purity Science)
Чистота: ≥99% (подтверждено методом высокоэффективной жидкостной хроматографии – HPLC)
Форма: Белый лиофилизированный порошок
Упаковка: Флакон фармацевтического класса для лабораторных исследований
Назначение: Только для лабораторного использования. Не для применения у людей или животных.

Введение в DSIP

DSIP (Delta Sleep-Inducing Peptide) — это природный нейропептид, впервые выделенный из мозга кроликов в 1977 году. Он активно изучается за его влияние на регуляцию сна, биоритмы и нейроэндокринные функции. DSIP состоит из девяти аминокислот, являясь нонапептидом с выраженной регулирующей и нейромодулирующей активностью.

Синтетическая форма DSIP, производимая HPS, изготавливается в строго контролируемых лабораторных условиях с чистотой ≥99%, подтверждённой HPLC. Препарат предназначен исключительно для научных исследований и обеспечивает высокую воспроизводимость и достоверность получаемых данных.

Ключевые характеристики

Высокая чистота: ≥99%, подтверждено методом HPLC
Лиофилизация фармацевтического класса для стабильного хранения
Надёжный производитель (HPS) с акцентом на лабораторные пептиды
Строгий контроль качества и отслеживаемость партий
Использование только в рамках доклинических и in vitro исследований

Биологическое значение DSIP

1. Регуляция сна
DSIP был открыт благодаря своей способности вызывать дельта-сон (медленные волны сна – SWS), не нарушая фазу быстрого сна (REM). Пептид может модулировать активность нейромедиаторов, таких как серотонин и норадреналин.

2. Эндокринная регуляция
DSIP влияет на секрецию следующих гормонов:

АКТГ (адренокортикотропный гормон)
ЛГ (лютеинизирующий гормон)
Соматотропин (гормон роста)
Также участвует в регуляции гипоталамо-гипофизарной оси.

3. Модуляция стресса
В экспериментах на животных DSIP снижал уровень кортикостерона, что указывает на его анксиолитическое и антистрессовое действие. Эффект, предположительно, связан с GABA- и серотонинергической системой.

4. Влияние на восприятие боли
DSIP может воздействовать на опиоидные рецепторы и изменять болевой порог.

5. Терморегуляция и циркадные ритмы
DSIP участвует в регуляции температуры тела и биологических ритмов, что делает его объектом интереса в хронобиологии и хрономедицине.

Области применения в исследованиях

Научная область	Объекты изучения
Нейробиология	Циклы сна, нейротрансмиттеры, восприятие боли
Эндокринология	Гормональный баланс, гормон роста
Психофармакология	Стресс, тревожность, депрессия
Хронобиология	Циркадные ритмы, биологические часы
Иммунология	Цитокины, иммунный ответ
Метаболизм	Энергетический обмен, скорость метаболизма

Производство и контроль качества от HPS

HPS (High Purity Science) применяет строгие стандарты GMP при синтезе пептидов. DSIP производится методом твёрдофазного пептидного синтеза (SPPS) в стерильных условиях при контролируемой температуре. Каждая партия проходит очистку и проверку с помощью HPLC, обеспечивая чистоту ≥99%.

Качественные параметры:

Чистота (HPLC): ≥99%
Уровень эндотоксинов: <0.1 EU/mg
Влажность: <6%
Растворимость: Растворим в воде, разбавленной уксусной кислоте или DMSO
Внешний вид: Белый лиофилизированный порошок
Хранение: –20 °C (для длительного хранения)

Каждая партия сопровождается сертификатом анализа (COA) с номером партии, сроком годности и HPLC-профилем.

HPLC-анализ (сводка)

Каждая партия DSIP проходит анализ HPLC, подтверждающий структуру пептида, чистоту и отсутствие загрязнений.

Параметр	Значение
Время удерживания	5,24 минуты
Чистота основного пика	≥99,03%
Обнаруженные примеси	<0,5%
Длина волны регистрации	220 нм

Анализ гарантирует надёжность и воспроизводимость результатов.

Варианты упаковки

Доступен в флаконах:

1 мг
2 мг
5 мг
Индивидуальные оптовые заказы — по запросу

Флаконы запечатаны в инертной среде (азот), защищены от света и упакованы вакуумно для максимальной стабильности.

Юридическая информация и меры безопасности

Продукт предназначен исключительно для научных исследований. Не предназначен для диагностики, лечения или применения у человека/животных. Неправомерное использование может повлечь юридическую ответственность.

Средства индивидуальной защиты (СИЗ) обязательны: перчатки, лабораторный халат, защитные очки. Использовать только в сертифицированной лаборатории под контролем квалифицированного персонала.

Почему выбирают HPS?

Компания HPS (High Purity Science) — признанный производитель лабораторных пептидов благодаря:

Сертификации ISO 9001:2015
Полной аналитической документации (COA, HPLC, масс-спектрометрия)
Прозрачности поставок и технической поддержке
Услугам по индивидуальному синтезу пептидов

Исследовательские институты, фармацевтические и биотехнологические компании по всему миру доверяют HPS за надёжность, качество и доступные цены.

Заключение

DSIP (Delta Sleep-Inducing Peptide) — перспективный пептид в области нейробиологии, эндокринологии и исследований сна. Производимый компанией HPS с чистотой ≥99% по HPLC, он обеспечивает высокую точность и воспроизводимость в доклинических исследованиях.

Благодаря строгим стандартам качества, HPS предлагает DSIP, которому можно доверять — с полной документацией и лабораторной упаковкой.

한글

DSIP (델타 수면 유도 펩타이드) – 고순도 실험실 전용 펩타이드 (≥99% HPLC) – 제조사: HPS

📦 제품 개요

제품명: DSIP (Delta Sleep-Inducing Peptide)
CAS 번호: 62568-57-4
분자식: C₃₅H₄₈N₁₀O₁₅
분자량: 848.81 g/mol
아미노산 서열: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
동의어: 델타 수면 유도 펩타이드, DSIP 펩타이드
제조사: HPS (High Purity Science)
순도: ≥99% (고성능 액체 크로마토그래피 HPLC로 검증됨)
형태: 백색 동결 건조 분말
포장: 제약 등급 실험용 바이알
사용 목적: 연구 전용 (인체 또는 동물에 사용 금지)

🧬 DSIP 소개

**DSIP (Delta Sleep-Inducing Peptide)**는 1977년 토끼의 뇌에서 처음 분리된 자연 발생성 신경 펩타이드입니다. 이 펩타이드는 수면 조절, 생체 리듬 및 신경내분비 조절과 관련된 연구에서 광범위하게 사용되고 있습니다. 9개의 아미노산으로 구성된 노나펩타이드로, 다양한 생리학적 조절 기능을 가지고 있습니다.

HPS에서 제조한 이 합성 DSIP는 엄격한 실험실 환경에서 제조되며, HPLC 분석을 통해 ≥99% 순도를 보장합니다. 신뢰도 높은 생리학적 및 신경과학 연구를 위한 이상적인 실험용 시약입니다.

✅ 주요 특징

고순도 ≥99%, HPLC로 검증
제약 등급 동결 건조로 장기 안정성 확보
HPS 제조 – 연구용 펩타이드 분야의 신뢰성 있는 브랜드
엄격한 품질 관리 및 생산 이력 추적 가능
오직 실험실 전용 (전임상 및 in vitro 연구에만 사용)

🧠 DSIP의 생물학적 중요성

1. 수면 조절
DSIP는 서파수면(SWS)을 촉진하는 효과로 처음 주목받았습니다. REM 수면에는 영향을 주지 않으며, 세로토닌 및 노르에피네프린 등 수면 관련 신경전달물질의 방출을 조절할 수 있습니다.

2. 내분비 조절
DSIP는 다음과 같은 호르몬의 분비에 영향을 미칠 수 있습니다:

부신피질자극호르몬 (ACTH)
황체형성호르몬 (LH)
성장호르몬 (GH)
이는 시상하부-뇌하수체 축의 조절과 관련이 있습니다.

3. 스트레스 완화
DSIP는 동물 실험에서 코르티코스테론 수치를 낮추는 효과를 보여주며, 불안 완화 및 항스트레스 작용과 연관이 있습니다. 이는 GABA 및 세로토닌 시스템과 관련되어 있을 수 있습니다.

4. 통증 인지
DSIP는 오피오이드 수용체 시스템을 조절하여 통증 민감도를 변화시킬 수 있습니다.

5. 체온 조절 및 생체리듬
DSIP는 체온 조절 및 생체 시계 기능에 관여하며, 크로노바이올로지 및 시간 의학(Chronotherapy) 분야에서 연구되고 있습니다.

🔬 연구 응용 분야

연구 분야	주요 응용
신경과학	수면 주기, 신경전달, 통증 조절
내분비학	호르몬 균형, 성장호르몬 관련 연구
정신약리학	스트레스, 불안, 우울증 모델
크로노바이올로지	생체 시계, 일주기 리듬 연구
면역학	면역 반응, 사이토카인 조절
대사 연구	에너지 균형, 대사율 조절

🏭 HPS의 제조 및 품질 관리

**HPS (High Purity Science)**는 고순도 펩타이드 합성을 위해 **GMP(우수제조관리기준)**을 준수합니다. DSIP는 고체상 펩타이드 합성(SPPS) 방식으로 무균 상태에서 제조되며, 다단계 정제와 HPLC를 통해 ≥99% 순도를 보장합니다.

품질 기준:

순도 (HPLC): ≥99%
엔도톡신 수준: <0.1 EU/mg
수분 함량: <6%
용해도: 멸균 증류수, 희석 아세트산, 또는 DMSO에 용해 가능
외관: 백색 동결건조 분말
보관 온도: –20 °C (장기 보관 시)

모든 제품에는 COA(시험성적서), 제조번호, 유통기한, HPLC 분석 정보가 포함됩니다.

📊 HPLC 분석 요약

각 로트는 다음과 같은 HPLC 분석을 통해 일관성과 안정성을 확인합니다:

항목	값
유지 시간	5.24분
피크 순도	≥99.03%
검출된 불순물	<0.5%
감지 파장	220 nm

이 분석은 실험 결과의 재현성과 신뢰성을 보장합니다.

🧪 재구성 및 보관 지침

재구성:
멸균 증류수, 0.9% 생리식염수, 또는 PBS 등 완충 용액에 녹여 사용하며, 실험 목적에 맞게 농도를 조절합니다.

보관:

동결건조 상태: –20 °C에서 24개월 이상 안정
재구성 후: 2–8 °C에서 보관하고 7–14일 이내 사용
재냉동/재해동은 피해야 함

📦 포장 옵션

HPS는 다음 용량으로 DSIP를 제공합니다:

1 mg
2 mg
5 mg
대량 주문 또는 맞춤형 포장 가능 (요청 시)

모든 바이알은 질소 플러시(Nitrogen-flushed) 상태로 진공 밀봉되며, 광 차단 처리로 안정성이 유지됩니다.

⚠️ 법적 고지 및 안전 지침

이 제품은 오직 실험실 연구 전용입니다. 인간 또는 동물의 진단, 치료 또는 소비 목적으로 사용해서는 안 됩니다. 사용 지침을 벗어난 활용은 법적 책임이 따를 수 있습니다.

실험 시 안전 보호구(PPE) 착용 필수 – 장갑, 실험복, 보호 안경. 전문 인력의 감독 하에 인증된 실험 환경에서만 사용해야 합니다.

🏆 왜 HPS를 선택해야 할까요?

**HPS (High Purity Science)**는 전 세계 수많은 연구 기관과 바이오테크 기업이 신뢰하는 펩타이드 공급업체입니다:

ISO 9001:2015 인증된 제조 공정
COA, HPLC, MS 포함한 완전한 분석 문서 제공
투명한 공급망 및 기술 지원
맞춤형 펩타이드 합성 서비스 제공

HPS는 고품질, 일관성, 경쟁력 있는 가격으로 전 세계 과학자들에게 선택받고 있습니다.

🔚 결론

**DSIP (Delta Sleep-Inducing Peptide)**는 신경과학, 내분비학, 수면 과학 분야에서 중요한 연구 도구입니다. HPS에서 제조한 DSIP는 ≥99% 순도의 HPLC 인증 제품으로, 다양한 전임상 모델에서 탁월한 실험 재현성을 보장합니다.

엄격한 품질 기준과 신뢰할 수 있는 생산 시스템을 바탕으로, HPS는 안정성, 순도, 연구 효율성을 모두 만족시키는 실험용 DSIP를 제공합니다.

日本語

DSIP（デルタ睡眠誘導ペプチド）— 高純度研究用ペプチド（≥99% HPLC）— 製造元：HPS

🧪 製品概要

製品名： DSIP（Delta Sleep-Inducing Peptide）
CAS番号： 62568-57-4
分子式： C₃₅H₄₈N₁₀O₁₅
分子量： 848.81 g/mol
アミノ酸配列： Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
別名： デルタ睡眠誘導ペプチド、DSIPペプチド
製造者： HPS（High Purity Science）
純度： ≥99%（高性能液体クロマトグラフィー（HPLC）により検証）
形状： 白色の凍結乾燥粉末
包装： 医薬品グレードの研究用バイアル
用途： 研究用途のみに限定（人または動物への使用は禁止）

🔬 DSIPとは？

DSIP（デルタ睡眠誘導ペプチド） は、1977年にウサギの脳から初めて単離された天然の神経ペプチドです。睡眠調節、生物学的リズム、神経内分泌調節への関与が広く研究されています。9個のアミノ酸からなるノナペプチドであり、神経調節・生理調節の機能を持っています。

HPS社製の合成DSIPは、厳格な研究環境の下で製造され、HPLCにより99%以上の純度が保証されています。生理学的・神経生物学的研究において高い再現性と信頼性を提供します。

✅ 主な特長

高純度（≥99%） — HPLCにより検証済
医薬品グレードの凍結乾燥 — 長期保存に最適
信頼性の高い製造元 — HPS（研究用ペプチドの専門メーカー）
厳格な品質管理とロット追跡
研究専用（in vitroおよび前臨床用途）

🧠 生理学的意義

1. 睡眠調節

DSIPは、**徐波睡眠（SWS）**を誘導する作用で知られ、REM睡眠には影響を与えません。セロトニンやノルアドレナリンなどの神経伝達物質の放出に関与すると考えられています。

2. 内分泌調節

以下のホルモン分泌に関与する可能性があります：

副腎皮質刺激ホルモン（ACTH）
黄体形成ホルモン（LH）
成長ホルモン（GH）

視床下部—下垂体系の調節に関連する可能性があります。

3. ストレス応答の緩和

動物モデルにおいて、DSIPはコルチコステロンのレベルを低下させ、不安抑制作用（アンキシオリティック）やストレス緩和効果を示しています。これはGABA作動系やセロトニン系の調節と関連している可能性があります。

4. 疼痛知覚の調整

オピオイド受容体系に作用し、痛覚閾値に影響を与える可能性があります。

5. 体温調節とサーカディアンリズム

DSIPは体温や生体リズムにも影響を与えると考えられ、**時間生物学（クロノバイオロジー）や時間療法（クロノセラピー）**における研究対象となっています。

📚 研究用途と応用領域

研究分野	応用例
神経科学	睡眠周期、神経伝達、疼痛調節
内分泌学	ホルモン分泌、成長ホルモン研究
精神薬理学	ストレス、不安、うつモデル
時間生物学	サーカディアンリズム、生体時計研究
免疫学	免疫応答、サイトカインの調節
代謝研究	代謝率、エネルギーホメオスタシスの関与

🏭 製造と品質管理（HPSによる）

**HPS（High Purity Science）**は、GMP（適正製造基準）に準拠し、**固相ペプチド合成（SPPS）**法によりDSIPを製造しています。すべてのロットは無菌かつ温度管理された環境下で生産され、HPLCによる純度検査が行われます。

品質管理項目：

HPLC純度： ≥99%
エンドトキシン濃度： <0.1 EU/mg
水分含有量： <6%
溶解性： 精製水、希酢酸、またはDMSOに可溶
外観： 白色凍結乾燥パウダー
保存温度： –20°C（長期保存）

製品にはすべて、**分析証明書（COA）**が付属し、ロット番号・有効期限・HPLC分析情報が記載されています。

📊 HPLC分析サマリー

分析項目	値
保持時間	5.24分
ピーク純度	≥99.03%
検出された不純物	<0.5%
検出波長	220 nm

HPLC分析は、試験の再現性・信頼性を支える重要な指標です。

💧 溶解および保存方法

溶解方法：
滅菌精製水、0.9%生理食塩水、PBSなどのバッファーで再構成。用途に応じて濃度を調整してください。

保存条件：

凍結乾燥状態： –20°Cで24ヶ月以上安定
再構成後： 2～8°Cで保存し、7〜14日以内に使用
再凍結・再解凍は避けること

📦 パッケージオプション

以下の容量で提供可能：

1mg バイアル
2mg バイアル
5mg バイアル
大口注文やカスタムパッケージも対応可能（要相談）

すべてのバイアルは、窒素置換・真空密封・遮光処理済み容器で出荷され、品質を最大限保持します。

⚠️ 法的注意・安全に関する情報

この製品は研究用途のみに使用可能です。診断・治療・ヒトまたは動物への投与には使用できません。研究指針を超えた不正使用には法的責任が生じる可能性があります。

個人用保護具（PPE）（手袋、実験用白衣、保護メガネなど）を着用し、認可された研究施設内で、適切な監督のもと取り扱ってください。

🏆 HPSを選ぶ理由

**HPS（High Purity Science）**は、世界中の研究機関・大学・製薬会社から信頼されているペプチドメーカーです：

ISO 9001:2015 認証取得済
HPLC・MS・COAを含む完全な分析書類付き
トレーサビリティと透明性の高い製造
オーダーメイドのペプチド開発にも対応

再現性、品質、コストパフォーマンスを重視する研究者に最適なパートナーです。

🔚 結論

**DSIP（デルタ睡眠誘導ペプチド）**は、神経科学・内分泌学・睡眠研究において大きな研究価値を持つペプチドです。HPSの高純度DSIP（≥99% HPLC）は、前臨床モデルでの信頼性と再現性を提供します。

品質へのこだわりと完全な分析サポートを備えたHPSのDSIPは、研究用途における最良の選択肢です。

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